Realistically, there are three main cities that deserve to find themselves on this list: Las Vegas, Macao and Atlantic City. Let’s start by taking a look at the cities themselves individually before we start to look at how they compare to each other. Are we looking at the physical size of the city? The turnover that each city enjoys on a yearly basis? The number of visitors that travel there? More importantly, are these factors different from each other? The Cities Obviously the answer to that depends on what metric it is that you’re using to decide upon what makes a city the ‘biggest’. It is synonymous with gambling and has been pretty much since the first ones began to open their doors there, but is it actually the biggest casino city in the world? Ask one hundred people to name a city where you’ll find a host of casinos and the vast majority of them will be sure to say Las Vegas.